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ChemInform Abstract: Diastereoselectivity in α-Benzylation Reactions of Esters of Spiro[bornane-3,2′-indan]-2-exo-ol.

✍ Scribed by M. D. EVANS; P. T. KAYE


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Diastereoselective
✍ Florence Roger; Marie-Gabrielle Le Pironnec; Michel Guerro; Patrick Gougeon; Phi 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

Diastereoselective Synthesis of N-(α-Aryl-α-haloacetyl) Amino Acid Esters by Acylation Using 3-Aryl-2,2-dicyanooxiranes. -α-Arylα-bromo ketenes are generated in situ starting from epoxides (I) by treatment with Li 2 NiBr 4 , followed by the addition of Et 3 N at -78 • C. Trapping of these intermedi