ChemInform Abstract: Nucleophilic Additi
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P. MERINO; E. CASTILLO; S. FRANCO; F. L. MERCHAN; T. TEJERO
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Article
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2010
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John Wiley and Sons
⚖ 38 KB
Nucleophilic Additions of Grignard Reagents to N-Benzyl-2,3-O-isopropylidene-D-glyceraldehyde Nitrone (BIGN). Synthesis of (2S,3R) and (2S,3S)-3-Phenylisoserine. -The addition of Grignard reagents to the nitrone (I) proceeds with high anti or syn selectivity depending on the Lewis acid used. The re