Design, Synthesis, and Molecular-modelin
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Mohga M. Badran; Maha Abdel Hakeem; Suzan M. Abuel-Maaty; Afaf El-Malah; Rania M
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Article
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2010
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John Wiley and Sons
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English
⚖ 820 KB
## Abstract 2‐Amino‐3‐cyanothiophenes were successfully condensed with a number of cycloalkanones to afford tacrine analogues in a one‐step reaction mediated with Lewis acid. The newly synthesized compounds have been tested for their ability to inhibit acetylcholine esterase (AChE) activity using t