ChemInform Abstract: Design, Synthesis and Evaluation of Substituted N-(3-Arylpropyl)-9,10-dihydro-9-oxoacridine-4-carboxamides as Potent MDR Reversal Agents in Cancer.

✍ Scribed by V. S. Velingkar; V. D. Dandekar

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 29 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201128154

✦ Synopsis

Abstract

A variety of new acridine‐4‐carboxamides (VII) and (IX) is designed, synthesized by a novel route and evaluated for their inhibitory effects on the transport activity of P‐glycoprotein.