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ChemInform Abstract: Design, Synthesis, and Biological Evaluation of 1,5-Diaryl-1,2,4-triazole Derivatives as Selective Cyclooxygenase-2 Inhibitors.

✍ Scribed by Bo Jiang; Yi Zeng; Meng-Jie Li; Jin-Yi Xu; Yong-Na Zhang; Qiu-Juan Wang; Ni-Yue Sun; Tao Lu; Xiao-Ming Wu

Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
41
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

The results of biological tests show that compound (I) is a potent and selective inhibitor of COX‐2 (IC~50~ = 0.37 ΞΌM) being equipotent to celecoxib.

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