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ChemInform Abstract: Design of Potent and Selective GPR119 Agonists for Type II Diabetes.

✍ Scribed by Jason W. Szewczyk; et al. et al.

Publisher: John Wiley and Sons
Year: 2012
Weight: 12 KB
Volume: 43
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201210175

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Dual termini optimization of a bis‐piperidine‐based GPR119 agonist affords an analogue possessing improved potency, selectivity, and formulation profile, but modest physical properties.

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