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ChemInform Abstract: Design of Monocyclic (1—3) and Dicyclic (1—3/4—10) Gonadotropin Releasing Hormone (GnRH) Antagonists.

✍ Scribed by Jean E. Rivier; John Porter; Laura A. Cervini; Sabine L. Lahrichi; Dean A. Kirby; R. Scott Struthers; Steven C. Koerber; Catherine L. Rivier


Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
31
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Design and Synthesi
✍ Ming Fai Chan; Bore G. Raju; Adam Kois; Jay I. Varughese; Kottayil I. Varughese; 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Design and Synthesis of 1,4-Diazabicyclo[4.3.0]nonane Peptidomimetic Endothelin Antagonists. -Four peptidomimetics such as (XI) are synthesized in order to examine the effect of the carboxyl group stereochemistry on the biological activity. The structures of the peptidomimetics are based on the pep