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ChemInform Abstract: Design, Evaluation and Structure—Activity Relationship Studies of the AChE Reactivators Against Organophosphorus Pesticides

✍ Scribed by Kamil Musilek; Martin Dolezal; Frank Gunn-Moore; Kamil Kuca

Publisher
John Wiley and Sons
Year
2011
Weight
18 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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Design, evaluation and structure—Activit
Design, evaluation and structure—Activity relationship studies of the AChE reactivators against organophosphorus pesticides
✍ Kamil Musilek; Martin Dolezal; Frank Gunn-Moore; Kamil Kuca 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 372 KB

## Abstract Organophosphate pesticides (OPPs; e.g. chlorpyrifos, diazinon, paraoxon) are a wide and heterogeneous group of organophosphorus compounds. Their biological activity of inhibiting acetylcholinesterase (AChE) or butyrylcholinesterase (BChE) ranks them as life endangering agents. The neces