## Abstract Various structurally modified analogues of FR235222 (**1**), a natural tetrapeptide inhibitor of mammalian histone deacetylases, were prepared in a convergent approach. The design of the compounds was aimed to investigate the effect of structural modifications of the tetrapeptide core i
ChemInform Abstract: Design and Synthesis of Histone Deacetylase Inhibitors: The Development of Apicidin Transition State Analogues.
β Scribed by Steven L. Colletti; Robert W. Myers; Sandra J. Darkin-Rattray; Dennis M. Schmatz; Michael H. Fisher; Matthew J. Wyvratt; Peter T. Meinke
- Publisher
- John Wiley and Sons
- Year
- 2000
- Weight
- 26 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract Review: 21 refs.