ChemInform Abstract: Derivatives of (R)-2-Amino-5-methoxytetralin: Antagonists and Inverse Agonists at the Dopamine D2A Receptor.
β Scribed by Berit Backlund Hoeoek; Cecilia Brege; Tero Linnanen; Aasa Mikaels; Aasa Malmberg; Anette M. Johansson
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 31 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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Herein, we evaluate the interaction of the β£ 2 -AR antagonist, yohimbine, as compared to fluparoxan, at multiple monoaminergic receptors and examine their roles in the modulation of adrenergic, dopaminergic and serotonergic transmission in freelymoving rats. Yohimbine displays marked affinity at hum