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ChemInform Abstract: Cyclooxygenase Inhibitors: Scope of Their Use and Development in Cancer Chemotherapy

✍ Scribed by Mohammed Naseer A. Khan; Yong Sup Lee

Publisher
John Wiley and Sons
Year
2011
Weight
18 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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πŸ“œ SIMILAR VOLUMES

Cyclooxygenase inhibitors: Scope of thei
Cyclooxygenase inhibitors: Scope of their use and development in cancer chemotherapy
✍ Mohammed Naseer A. Khan; Yong Sup Lee πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 397 KB

## Abstract The traditional nonsteroidal anti‐inflammatory drugs (NSAIDs) exert their effect by inhibition of cyclooxygenase‐1 (COX‐1) as well as COX‐2 enzymes. As COX‐1 is responsible for maintaining normal biological functions, the nonselective inhibition of these enzymes caused side effects incl