ChemInform Abstract: Cycloaddition Reactions of Aldimines of 1,5-Ketoaldehydes. Applications in the Synthesis of Polycyclic Nitrogen Heterocycles.

✍ Scribed by Ronald Grigg; Mark Thornton-Pett; Gnanamoly Yoganathan

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 35 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199927160

✦ Synopsis

Cycloaddition Reactions of Aldimines of 1,5-Ketoaldehydes. Applications in the Synthesis of Polycyclic Nitrogen Heterocycles.

-Treatment of aldimines of 1,5-ketoaldehydes with methyl acrylate in the presence of AgOAc/DBU or LiBr/DBU results in formation of pyrrole derivatives. Subsequent acid-catalyzed cyclization leads to tricyclic and/or tetracyclic ring systems depending on the educt structure.

-(GRIGG, RONALD;