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ChemInform Abstract: Cycloaddition of 3-Amino-5-chloro-2(1H)-pyrazinones and Olefins: Ring Transformation into 3-Amino- or 6-Cyano-Substituted 2-Pyridinone Systems.

โœ Scribed by S. M. VANDENBERGHE; K. J. BUYSENS; L. MEERPOEL; P. K. LOOSEN; S. M. TOPPET; G. J. HOORNAERT


Book ID
112031797
Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
27
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Ring Transformation
โœ T. UEDA; S. ASAI; K. OIJI; S. NAGAI; A. NAGATSU; J. SAKAKIBARA ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 2 views

Ring Transformation of 5-Amino (or Acylamino)-6-hydroxy (or benzoyloxy) methylpyrimidin-4(3H)-ones into 1H-Imidazoles. -Substituted pyrimidinones (I) and (III) readily undergo a ring contraction reaction in the presence of sodium hydroxide yielding the corresponding imidazole derivatives (II) and (