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ChemInform Abstract: Cyanoacetamide in Heterocyclic Chemistry: Synthesis, Antitumor and Antioxidant Activities of Some New Benzothiophenes.

✍ Scribed by Serry A. A. El Bialy; Moustafa A. Gouda


Book ID
112043115
Publisher
John Wiley and Sons
Year
2012
Weight
37 KB
Volume
43
Category
Article
ISSN
0931-7597

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Cyanoacetamide in heterocyclic chemistry
✍ Serry A. A. El Bialy; Moustafa A. Gouda 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 372 KB

## Abstract Cyanoacylation of 2‐amino‐tetrahydrobenzothiophene‐3‐carboxylate ethyl ester with 3‐(3,5‐dimethyl‐1__H__‐pyrazol‐1‐yl)‐3‐oxopropanenitrile afforded cyanoacetamide **2**. The later was utilized as key intermediate for the synthesis of 3‐substituted 2‐iminocoumarins **3**, **4**, **5**, *