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ChemInform Abstract: Critical Importance of the Nine-Membered F Ring of Ciguatoxin for Potent Bioactivity: Total Synthesis and Biological Evaluation of F-Ring-Modified Analogues.

✍ Scribed by Masayuki Inoue; Nayoung Lee; Keisuke Miyazaki; Toyonobu Usuki; Shigeru Matsuoka; Masahiro Hirama

Publisher
John Wiley and Sons
Year
2009
Weight
15 KB
Volume
40
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.

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Critical Importance of the Nine-Membered
Critical Importance of the Nine-Membered F Ring of Ciguatoxin for Potent Bioactivity: Total Synthesis and Biological Evaluation of F-Ring-Modified Analogues
✍ Masayuki Inoue; Nayoung Lee; Keisuke Miyazaki; Toyonobu Usuki; Shigeru Matsuoka; πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 541 KB

Trans-fused polycyclic ethers such as ciguatoxins and brevetoxins are among the most spectacular classes of compounds isolated from marine sources (Scheme 1). [1] These molecules are made up of a single carbon chain locked into a ladderlike structure with a length of 3 nm. The striking regularity wi