ChemInform Abstract: Copper-Mediated Fluoroalkylation Reactions with [(Phenylsulfonyl)difluoromethyl]trimethylsilane: Synthesis of PhSO2CF2-Containing Allenes and Alkynes.

✍ Scribed by Jieming Zhu; Fei Wang; Weizhou Huang; Yanchuan Zhao; Wenchao Ye; Jinbo Hu

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 34 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201133074

✦ Synopsis

Abstract

The new Ph‐SO~2~‐CF~2~Cu species, formed in situ from starting compound (I) under conditions A, undergoes cross‐coupling reactions with propargyl chlorides (II) and alkynyl iodides (IV) to afford phenylsulfonyldifluoromethyl‐containing allenes (III) and alkynes (V), respectively.