ChemInform Abstract: Convenient Method for Synthesis of Thiazolo[3,2-a]pyrimidine Derivatives in a One-Pot Procedure.

✍ Scribed by Sukhdeep Singh; Andreas Schober; Michael Gebinoga; G. Alexander Gross

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 31 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201144162

✦ Synopsis

Abstract

Careful α‐bromination of ketones with elemental bromine and direct addition of pyrimidine‐2‐thiones and triethylamine renders possible a direct two‐step one‐pot synthesis of the title compounds.