ChemInform Abstract: Continuous Flow Thermolysis of Azidoacrylates for the Synthesis of Heterocycles and Pharmaceutical Intermediates.

✍ Scribed by Alexander G. O'Brien; Francois Levesque; Peter H. Seeberger

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 31 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201126118

✦ Synopsis

Abstract

A scalable procedure for the thermolysis of azidoacrylates in a flow reactor is elaborated and applied for the synthesis of pyrroles, indoles, and related heterocycles.