✦ LIBER ✦
ChemInform Abstract: Conjugated Macrocycles Related to the Porphyrins. Part 17. Oxidation with Dilute Aqueous Ferric Chloride Solutions Greatly Improves Yields in the [4 + 1] Synthesis of Sapphyrins.
✍ Scribed by Daniel T. Richter; Timothy D. Lash
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 35 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Conjugated Macrocycles Related to the Porphyrins. Part 17. Oxidation with Dilute Aqueous Ferric Chloride Solutions Greatly Improves Yields in the [4 + 1] Synthesis of Sapphyrins.
-The '4+1' route to porphyrins is extremely improved by use of 0.1% aqueous ferric chloride as oxidant in place of DDQ, e.g. the yield of derivative (IIIe) is increased from 16% (DDQ) to 74% (FeCl 3 ). The yields of carbasapphyrins (IV) are lower (12-38%) but also greatly benefited from this approach. -(