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ChemInform Abstract: Conjoint Molecules of Cephalosporins and Aminoglycosides

✍ Scribed by Ioannis Grapsas; Stephen A. Lerner; Shahriar Mobashery

Publisher: John Wiley and Sons
Year: 2010
Weight: 27 KB
Volume: 33
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200204239

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Conjoint molecules of cephalosporins and

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## Conjoint molecules of cephalosporins and aminoglycosides A general synthetic route to conjoint molecules of cephalosporins and aminoglycosides is described. These molecules were designed as potential substrates for bacterial β-lactamases, enzymes that hydrolyze the β-lactam bond of cephalospori

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