✦ LIBER ✦

ChemInform Abstract: Conformationally Restricted Butyrophenones with Mixed Dopaminergic (D2) and Serotoninergic (5-HT2A) Affinities. Synthesis of 5-Aminoethyl- and 6-Aminomethyl-4-oxotetrahydroindoles as Potential Atypical Antipsychotics.

✍ Scribed by Christian F. Masaguer; Isabel Casariego; Enrique Ravina

Publisher: John Wiley and Sons
Year: 2010
Weight: 40 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199946130

No coin nor oath required. For personal study only.

✦ Synopsis

Conformationally Restricted Butyrophenones with Mixed Dopaminergic (D 2 ) and Serotoninergic (5-HT 2A ) Affinities.

Synthesis of 5-Aminoethyl-and 6-Aminomethyl-4-oxotetrahydroindoles as Potential Atypical Antipsychotics.

-In continuation of an earlier study, compounds such as (X) and (XV) are synthesized having the titled biological activity. The most interesting compounds (Xc) and (Xd), named QF 0408B and QF 0409B, resp., are chosen for further development. -(MASAGUER,

📜 SIMILAR VOLUMES

ChemInform Abstract: Butyrophenone Analo

ChemInform Abstract: Butyrophenone Analogues in the Carbazole Series as Potential Atypical Antipsychotics: Synthesis and Determination of Affinities at D2, 5-HT2A, 5-HT2B and 5-HT2C Receptors.

✍ Christian F. Masaguer; Enrique Ravina; Jose Angel Fontenla; Jose Brea; Helena Tr 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 38 KB 👁 1 views

ChemInform Abstract: New Cyclic Butyroph

ChemInform Abstract: New Cyclic Butyrophenone Derivatives in the Indole Series as Potential Atypical Antipsychotics. A Simple and Practical Synthesis of 6- Aminomethyl-tetrahydroindol-4-ones and Their Affinities for D2 and 5- HT2A Receptors.

✍ C. F. MASAGUER; E. RAVINA; I. LOZA; J. A. FONTENLA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views