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ChemInform Abstract: Conformationally Constrained Dipeptides. Obtention of Enantiomerically Pure 6-Acetamido-5-oxo-1,2,3,5,6,7-hexahydro-3-indolizine Carboxylic Acid.

✍ Scribed by Regis Millet; Emmanuelle Meulon; Laurence Goossens; Raymond Houssin; Jean-Pierre Henichart; Benoit Rigo


Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
32
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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πŸ“œ SIMILAR VOLUMES


Conformationally constrained dipeptides.
✍ RΓ©gis Millet; Emmanuelle Meulon; Laurence Goossens; Raymond Houssin; Jean-Pierre πŸ“‚ Article πŸ“… 2000 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 276 KB

## Abstract The separation of a stereoisomeric mixture of esters 6, and the synthesis of the new enantiomerically pure unsaturated 6,5‐fused bicyclic lactam 2 are described. The key‐step involves trimethylsilyl iodide cleavage, without racemization, of a vinylogous carbamate. The __cis N‐__ acetyla

ChemInform Abstract: Synthesis and Excha
✍ C. A. BATTY; M. K. MANTHEY; J. KIRK; M. MANTHEY; R. I. CHRISTOPHERSON; T. HAMBLE πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 35 KB πŸ‘ 2 views

Synthesis and Exchange Reactions of 5-Alkyl-2-oxo-6-thioxo-1,2,3,6-Tetrahydropyrimidine-4-carboxylic Acids. -The title compounds are prepared as potential dihydroorotase inhibitors. H/D-exchange studies establish a high tendency towards epimerization at C-5. No epimerization is observed under physi