✦ LIBER ✦
ChemInform Abstract: Concise Stereoselective Synthesis of 1-Perfluoroalkyl Enamines via the Addition of N-Lithiated Amines to Enol Ethers and Their Subsequent Metalation to Form New Functionalized Enamines.
✍ Scribed by J.-P. BEGUE; D. BONNET-DELPON; D. BOUVET; M. H. ROCK
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Concise Stereoselective Synthesis of 1-Perfluoroalkyl Enamines via the Addition of N-Lithiated Amines to Enol Ethers and Their Subsequent Metalation to Form New Functionalized Enamines.
-Addition of lithium amides (II) to (Z)-enol ethers (I) provides stereoselectively the corresponding (Z)-enamines (III) which can react with tBuLi and several electrophiles to provide new functionalized enamines (V) and (VII). -(BE-