ChemInform Abstract: Concise Preparation of 1,8-Diazaanthracene-2,7,9,10-tetraones. Two Alternative Syntheses of the Natural Antifolate Diazaquinomycin A.

Concise Preparation of 1,8-Diazaanthrace

Concise Preparation of 1,8-Diazaanthracene-2,7,9,10-Tetraones. Two Alternative Syntheses of the Natural Antifolate Diazaquinomycin A

✍ José Marı́a Pérez; Pilar López- Alvarado; Eva Pascual-Alfonso; Carmen Avendaño; 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 185 KB

AbstractÐTreatment of compounds bearing one or two 1-dimethylamino-1,4-dihydropyridine moieties with the urea-hydrogen peroxide complex (UHP) led to their ef®cient aromatization. Double N-oxidation of 1,8-diazaanthraquinones thus obtained is the ®rst example of a double N-oxidation of a diaza hetero