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ChemInform Abstract: Combined Fmoc-Alloc Strategy for a General Solid Phase Synthesis of Phosphoserine Peptides.

✍ Scribed by G. SHAPIRO; D. BUECHLER; C. DALVIT; M. DEL CARMEN FERNANDEZ; B. GOMEZ-LOR; E. POMBO-VILLAR; U. STAUSS; R. SWOBODA

Book ID
112033394
Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
27
Category
Article
ISSN
0931-7597

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Combined Fmoc-Alloc strategy for a gener
Combined Fmoc-Alloc strategy for a general solid phase synthesis of phosphoserine peptides
✍ Gideon Shapiro; Dieter BΓΌchler; Claudio Dalvit; Maria del Carmen Fernandez; Bert πŸ“‚ Article πŸ“… 1996 πŸ› Elsevier Science 🌐 English βš– 371 KB

A building block method for the SPPS of serine phosphopeptides has been developed using a combination of Fmoc and Alloc strategies. AIIoc-Ser[PO(OCH2CH=CH2)2]-OH , prepared in a one-pot procedure from Alloe-Ser-OH, was introduced at the Nterminus of a sequence prepared by standard Fmoc-SPPS. Global