ChemInform Abstract: Cobalt(0)-Mediated Addition of α-Haloesters and α-Haloketones to (R)-2,3-O-Cyclohexylideneglyceraldehyde.

✍ Scribed by F. ORSINI; C. LECCIOLI

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 36 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199820049

✦ Synopsis

1998 stereochemistry stereochemistry (general, optical resolution) O 0030 20 -049 Cobalt(0)-Mediated Addition of α-Haloesters and α-Haloketones to (R)-2,3-O-Cyclohexylideneglyceraldehyde.

-Cobalt-mediated Reformatsky-type and aldol-type additions of α-halocarbonyls to protected glyceraldehyde proceed smoothly both under stoichiometric and substoichiometric conditions with respect to cobalt. The investigation is presented with a view to developing a flexible route to monosaccharides. -(ORSINI, F.;