✦ LIBER ✦
ChemInform Abstract: Click to a Focused Library of Benzyl 6-Triazolo(hydroxy)benzoic Glucosides: Novel Construction of PTP1B Inhibitors on a Sugar Scaffold.
✍ Scribed by Cui Li; Xiao-Peng He; Yin-Jie Zhang; Zhen Li; Li-Xin Gao; Xiao-Xin Shi; Juan Xie; Jia Li; Guo-Rong Chen; Yun Tang
- Publisher
- John Wiley and Sons
- Year
- 2012
- Weight
- 37 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
Azides (III) bearing alkyl chain lengths ranging from 3 to 5C are synthesized from methyl hydroxylbenzoates, e.g. (I), via a straightforward two‐step sequence involving O‐alkylation followed by nucleophilic azide substitution.