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ChemInform Abstract: Cinchona Alkaloid Catalyzed Enantioselective Direct Aldol-Type Reaction of Oxinoles with Ethyl Trifluoropyruvate.

✍ Scribed by Shinichi Ogawa; Norio Shibata; Junji Inagaki; Shuichi Nakamura; Takeshi Toru; Motoo Shiro


Publisher
John Wiley and Sons
Year
2008
Weight
52 KB
Volume
39
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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Cinchona Alkaloid-Catalyzed Enantioselec
✍ Fabio Pesciaioli; Paolo Righi; Andrea Mazzanti; Chiara Gianelli; Michele Mancine πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 229 KB πŸ‘ 1 views

The first enantioselective direct aldol addition of N-Boc-oxindoles to polymeric ethyl glyoxylate is presented. The reaction is performed by using as low as 0.1 mol% (DHQ) 2 PHAL and gives access to a-hydroxycarboxylate derivatives bearing adjacent secondary alcohol and quaternary stereocenters with