ChemInform Abstract: Chlorophenylmethyl Benzothiadiazine Dioxides Derivatives: Potent Human Cytomegalovirus Inhibitors.
β Scribed by Ana Martinez; Carmen Gil; Concepcion Perez; Ana Castro; Columbiana Prieto; Joaquin Otero
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 30 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0931-7597
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Discovery of 1,6-Naphthyridines as a Novel Class of Potent and Selective Human Cytomegalovirus Inhibitors. -A series of 20 1,6-naphthyridines, e.g. (I), is synthesized by amidation of key intermediate (IV) and in case of its halogen analogue (V) by subsequent Stille coupling with stannanes, e.g. (V