ChemInform Abstract: Chiroptical Properties of the Protoverbine Class of Macrocyclic Spermine Alkaloids.
β Scribed by K. DRANDAROV; A. GUGGISBERG; A. LINDEN; M. HESSE
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 24 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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The 17-membered macrocyclic spermine alkaloids protoverbine ((8S)-8-phenyl-1,5,9,13-tetraazacycloheptadecan-6-one, 1) and its N(9),N(13)-methylene-bridged derivative protomethine ((2S)-2-phenyl-1,5,9, 14tetraazabicyclo[12.3.1]octadecan-4-one, 2) were isolated from Verbascum pseudonobile Stoj. et Ste
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Dedicated to Prof. Hans-JΒΈrgen Hansen on the occasion of his 65th birthday Asymmetric syntheses of the following 17-membered macrocyclic spermine alkaloids are presented: (Γ)-(S)-protoverbine ( (8S)-8-phenyl-1,5,9,13-tetraazacycloheptadecane-6-one; 1), ()-(S)-protomethine ( (2S)-2-phenyl-1,5,9,14-te