ChemInform Abstract: Chiral Phosphoric Acid Catalyzed Addition of Dihydropyrans to N-Acyl Imines: Stereocontrolled Access to Enantioenriched Spirocyclic Oxazoletetrahydropyrans with Three Contiguous Stereocenters.

✍ Scribed by Guilong Li; Matthew J. Kaplan; Lukasz Wojtas; Jon C. Antilla

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 94 KB
• Volume: 41
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201037088

✦ Synopsis

Abstract

The first catalytic asymmetric addition of dihydropyran derivatives to N‐acyl imines proceeds with high yields and enantioselectivities.