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ChemInform Abstract: Chiral Organometallic Reagents. Part 18. Diastereoselective Bromine/ Lithium Exchange Reactions of 3-Alkoxy-1,1-dibromo-alkanes.

โœ Scribed by R. W. HOFFMANN; H.-C. STIASNY; J. KRUEGER


Book ID
112037554
Publisher
John Wiley and Sons
Year
2010
Weight
34 KB
Volume
27
Category
Article
ISSN
0931-7597

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Chiral Organometallic Reagents, I Stereo
โœ Hoffmann, Reinhard W. ;Bewersdorf, Martin ;Kr รผger, Michael ;Mikolaiski, Wolfgan ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 999 KB

Bromine-lithium exchange in l,l-dibromo-3-(trimethylsilyl-silylating agents. Diastereoselectivity in the generation and oxy)alkanes 4 and 6 affords the carbenoids 8 and 14, which trapping of the carbenoids ranged between 70 -90% for 8 and have been added to ketones, aldehydes, arylboronates, and >90