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ChemInform Abstract: Chiral HPLC for Efficient Resolution of Enantiomers

✍ Scribed by Yoshio Okamoto; Tomoyuki Ikai

Publisher
John Wiley and Sons
Year
2009
Weight
15 KB
Volume
40
Category
Article
ISSN
0931-7597

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Chiral recognition mechanism for the res
Chiral recognition mechanism for the resolution of enantiomers on a highly effective HPLC chiral stationary phase derived from (R)-4-hydroxyphenylglycine
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A chiral stationary phase (CSP 1) prepared starting from (R)-4hydroxyphenylglycine and then grafting (R)-N-butanoyl-4-allyloxyphenylglycine Npropyl amide to silica gel was found to be very effective in separating the enantiomers of N-(3,5-dinitrobenzoyl)-␣-amino amides. From the chromatographic beha