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ChemInform Abstract: Chemoselective O-Methylation of N-Acylated/Sulfonylated Tyrosine Derivatives.

โœ Scribed by Mireille Attolini; Thierry Boxus; Stephane Biltresse; Jacqueline Marchand-Brynaert


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
33
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Chemoselective O-Me
โœ A. BASAK; M. K. NAYAK; A. K. CHAKRABORTI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 2 views

Chemoselective O-Methylation of Phenols under Nonaqueous Condition. -A highly selective O-alkylation of various phenols (I) (24 examples) is achieved using 0.5 equivalents of dialkylsulfate [cf. (II)] in dry THF in the presence of LiOH as base. Use of other alkali or alkaline earth metal hydroxides