ChemInform Abstract: Chemoselective and Enantioselective Oxidation of Indoles Employing Aspartyl Peptide Catalysts.
โ Scribed by Filip Kolundzic; Mohammad N. Noshi; Meiliana Tjandra; Mohammad Movassaghi; Scott J. Miller
- Publisher
- John Wiley and Sons
- Year
- 2011
- Weight
- 34 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
Abstract
A striking โmatchedโ double asymmetric induction is observed when enantioenriched 2โarylindoles such as (I) are oxidized in the presence of a peptideโcatalyst and a coupling agent.
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## Abstract Either enantiomeric alkylated indole (III) can be selectively obtained in the presence of a copper catalyst derived from dihydroxylated brucine.
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