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ChemInform Abstract: Chemoenzymatic Synthesis of a Trisaccharide—Serine Conjugate, Gal(β1-3)Gal(β1-4)Xyl(β1-O)—L-Ser, Use of Galactosyl Fluoride as a Donor for Transglycosylation.

✍ Scribed by Koichi Fukase; Takashi Yasukochi; Shoichi Kusumoto


Publisher
John Wiley and Sons
Year
2010
Weight
29 KB
Volume
32
Category
Article
ISSN
0931-7597

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Abstract

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Synthesis of Protected Hexp-(1 → 4)-β-D-GlcpNAc-(1 → 2)-α-D-Manp-(1 → O)(CH2)7CH3 Sequences (Hex: β-D-Glc, 4-deoxy-4fluoro-β-D-Gal, or 4-deoxy-β-D-Gal) Using a Glc-GlcNPhth Donor, Eventually Fluorinated or Deoxygenated at the Oligosaccharide Level. -The title trisaccharide derivatives are prepared