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ChemInform Abstract: Cell Type Specific Recognition of the Reconstituted Aggregates from Isolated Type I Collagen, Type IV Collagen, and Type V Collagen

✍ Scribed by Toshihiko Hayashi; Kazunori Mizuno; Motohiro Hirose; Koichi Nakazato; Eijiro Adachi; Yasutada Imamura; Hiroaki Kosugi; Kiwamu Yoshikawa


Publisher
John Wiley and Sons
Year
2010
Weight
25 KB
Volume
30
Category
Article
ISSN
0931-7597

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## Abstract ## Objective Type II collagen (CII) is a candidate autoantigen implicated in the pathogenesis of rheumatoid arthritis (RA). Posttranslational glycosylation of CII could alter intracellular antigen processing, leading to the development of autoimmune T cell responses. To address this po