ChemInform Abstract: Catalytic Enantioselective Michael Addition of 1-Fluoro-bis(phenylsulfonyl)methane to α,β-Unsaturated Ketones Catalyzed by Cinchona Alkaloids.
✍ Scribed by Tatsuya Furukawa; Norio Shibata; Satoshi Mizuta; Shuichi Nakamura; Takeshi Toru; Motoo Shiro
- Publisher
- John Wiley and Sons
- Year
- 2009
- Weight
- 35 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Abstract
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## Abstract Asymmetric 1,4‐Michael additions of malononitrile and nitromethane to a wide spectrum of α,β,γ,δ‐unsaturated aryl ketones assisted by organocatalysis by bifunctional cinchona alkaloids is developed.