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ChemInform Abstract: Catalytic Enantioselective C—H Functionalization of Indoles with α-Diazopropionates Using Chiral Dirhodium(II) Carboxylates: Asymmetric Synthesis of the (+)-α-Methyl-3-indolylacetic Acid Fragment of Acremoauxin A.

✍ Scribed by Takayuki Goto; Yoshihiro Natori; Koji Takeda; Hisanori Nambu; Shunichi Hashimoto


Publisher
John Wiley and Sons
Year
2011
Weight
62 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

The title reaction provides a variety of N‐Mom‐protected α‐methyl‐3‐indolylacetates (III) in moderate enantioselectivities up to 86%.