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ChemInform Abstract: Catalytic Enantioselective Arylation of Aldehydes by Using Functionalized Grignard Reagents Generated from Aryl Bromides.

โœ Scribed by Daisuke Itakura; Toshiro Harada


Book ID
112042810
Publisher
John Wiley and Sons
Year
2012
Weight
33 KB
Volume
43
Category
Article
ISSN
0931-7597

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Catalytic Enantioselective Synthesis of
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## Abstract A general method has been developed for preparing enantioenriched secondary alcohols by starting from aryl bromides and aldehydes. Aryl bromides were first treated with BuLi, and the resulting aryllithium reagents were mixed with titanium tetraisopropoxide and magnesium bromide. The rea