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ChemInform Abstract: Catalytic Enantioselective Annulation Using Phenylsulfanylmethyl Vinyl Ketone. An Approach to trans-Hydrindan Building Blocks for ent-Vitamin D3 Synthesis.

✍ Scribed by Agnieszka Przezdziecka; Wiaczeslaw Stepanenko; Jerzy Wicha


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Catalytic Enantioselective Annulation Using Phenylsulfanylmethyl Vinyl Ketone. An Approach to trans-Hydrindan Building Blocks for ent-Vitamin D 3 Synthesis.

-Based on the enantioselective phenylalanine-catalyzed annulation of 2-methyl-1,3-cyclopentadione (II) with phenylsulfanylmethyl vinyl ketone (I), an asymmetric synthesis of building blocks [cf. (VI)] for the synthesis of vitamin D analogues is reported. -