ChemInform Abstract: Catalytic Enantioselective 1,6-Conjugate Addition of Grignard Reagents to Linear Dienoates.
β Scribed by Tim den Hartog; Syuzanna R. Harutyunyan; Daniel Font; Adriaan J. Minnaard; Ben L. Feringa
- Publisher
- John Wiley and Sons
- Year
- 2008
- Weight
- 36 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0931-7597
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Catalytic Enantioselective Conjugate Addition of Grignard Reagents to Cyclic Ξ±,Ξ²-Unsaturated Carbonyl Compounds. -The outcome of the title reaction is influenced by many factors such as amount and structure of the chiral phosphine, copper salt, Grignard reagent, as well as the solvent used.
## Abstract The use of FeCl~2~ as the catalyst yields mixtures of E/Zβolefins except in the case of substrates (VI), where only the (Z) isomers are formed.
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