ChemInform Abstract: Catalytic Asymmetric Hetero-Diels—Alder Reactions of Ketones: Chemzymatic Reactions.
✍ Scribed by S. YAO; M. JOHANNSEN; H. AUDRAIN; R. G. HAZELL; K. A. JOERGENSEN
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 35 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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Asymmetric Hetero-Diels-Alder Reactions with Heterocumulenes. -Chiral 2-alkenyloxazolines or thiazolines (I) and (IV) undergo hetero-Diels-Alder reaction with the ketene (II) or the isocyanate (VI) giving adducts with complete stereocontrol. In the case of oxazoline (I) a fast second addition yield
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