ChemInform Abstract: Catalytic Asymmetric Borane Reduction of Prochiral Ketones by the Use of Chiral β-Diamines.
✍ Scribed by Masatoshi Asami; Shinsuke Sato; Hiroyasu Watanabe
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 30 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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Easily available D-(+)-camphor-derived chiral mercapt\*alcohols 2 and 3 were employed for catalytic asymmetric borane reduction of aromatic ketones. Moderate enantioselectivities with e.e. 20.2-72.1% were obtained with 10 mol% catalyst. Opposite asymmetric induction was achieved' when mercaptc-alcoh
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