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ChemInform Abstract: Catalyst Free Three-Component Synthesis of (.+-.)-Pyrazolylpyrrolopyrroles by 1,3-Dipolar Cycloaddition Reaction.

✍ Scribed by Jairo Quiroga; Jaime Galvez; Alfredo Perez; Angela Valencia; Rodrigo Abonia; Braulio Insuasty


Publisher
John Wiley and Sons
Year
2012
Weight
31 KB
Volume
43
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

A simple one‐pot procedure allows the synthesis of title compounds (IV) via endo‐selective 1,3‐dipolar cycloaddition of ylides, generated in situ from aldehydes (I) and esters (II), with 1‐arylmaleimides (III).


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## Abstract Several bisphosphonate esters (III) bearing a substituted isoxazolidine moiety are synthesized in the absence of any solvent in good yields and short reaction times.