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ChemInform Abstract: Carbohydrate-Based Small-Molecule Scaffolds for the Construction of Universal Pharmacophore Mapping Libraries.

✍ Scribed by M. J. SOFIA; R. HUNTER; T. Y. CHAN; A. VAUGHAN; R. DULINA; H. WANG; D. GANGE


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


Carbohydrate-Based Small-Molecule Scaffolds for the Construction of Universal Pharmacophore Mapping Libraries. -Two monosaccharide scaffolds (IV) and (V), possessing three sites of diversification, the carboxylic acid moiety, the free hydroxyl function, and the protected amino group, are prepared as potential platforms for the preparation of carbohydrate-based universal pharmacophore mapping libraries. -(SOFIA, M.