ChemInform Abstract: C-Glycoside Phosphoramidite Building Block for Versatile Functionalization of Oligodeoxyribonucleotides.

✍ Scribed by J. HOVINEN; H. SALO

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 27 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199807243

✦ Synopsis

C-Glycoside Phosphoramidite Building Block for Versatile Functionalization of Oligodeoxyribonucleotides.

-Starting from 2-deoxy-D-ribose the interesting title synthon (I) is synthesized in six steps. The usefulness of this building block is shown in a machine-assisted synthesis of an oligonucleotide in which the synthon is used in the middle of the sequence.