ChemInform Abstract: Broensted Acid Assisted Regio- and Enantioselective Direct O-Nitroso Aldol Reaction Catalyzed by α,α-Diphenylprolinol Trimethylsilyl Ether.

✍ Scribed by Antonia Mielgo; Irene Velilla; Enrique Gomez-Bengoa; Claudio Palomo

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 52 KB
• Volume: 41
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201047024

✦ Synopsis

Abstract

The α‐oxyaldehyde adducts formed by the title reaction are generally unstable and isolated as the corresponding alcohols with essentially complete enantioselectivity after reduction with NaBH~4~.