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ChemInform Abstract: BMS-200475, a Novel Carbocyclic 2′-Deoxyguanosine Analogue with Potent and Selective anti-Hepatitis B Virus Activity in Vitro.

✍ Scribed by G. S. BISACCHI; S. T. CHAO; C. BACHARD; J. P. DARIS; S. INNAIMO; G. A. JACOBS; O. KOCY; P. LAPOINTE; A. MARTEL; Z. MERCHANT; W. A. SLUSARCHYK; J. E. SUNDEEN; M. G. YOUNG; R. COLONNO; R. ZAHLER

Publisher
John Wiley and Sons
Year
2010
Weight
38 KB
Volume
28
Category
Article
ISSN
0931-7597

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✍ Norman M. Kneteman; Anita Y. M. Howe; Tiejun Gao; Jamie Lewis; Dan Pevear; Gary 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 248 KB

## Anti -hepatitis C virus (HCV) drug development has been challenged by a lack of experience with inhibitors inclusive of in vitro, animal model, and clinical study. This manuscript outlines activity and correlation across such a spectrum of models and into clinical trials with a novel selective