ChemInform Abstract: Biotransformation of a Taxadiene by Ginkgo Cell Cultures and the Tumor Multi-Drug Resistant Reversal Activities of the Metabolites.

✍ Scribed by Dan Xie; Yi Zhang; Jianhua Zou; Dali Yin; Xiaoguang Chen; Jungui Dai

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 28 KB
• Volume: 43
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201203176

✦ Synopsis

Abstract

Biotransformation of 2α,5α,10β‐triacetoxy‐14‐oxa‐taxa‐4(20),11‐diene by cultured Gingko cells affords three new metabolites (I)—(III) along with a known taxadiene derivative.